PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA AND THE HIGH-FREQUENCY ULTRASOUND AS A DIAGNOSTIC TOOL

Abstract

This case report describes the use of high-frequency ultrasound (HFUS) as a diagnostic tool for cutaneous lymphomas. Cutaneous lymphomas are classified into T-cell and B-cell lymphomas, with B-cell lymphomas characterised by few lesions with rapid growth. The patient in this case report presented with an intensely vascularized reddish-brown nodule on the left shoulder. HFUS revealed a heterogeneous tumour lesion located in the epidermis and subcutaneous, infiltrating the adjacent muscles with increased vascularization. Computed tomography (CT) confirmed the presence of an expansive lesion. Anatomopathological examination revealed a primary cutaneous follicle center lymphoma. A finding of interest was the presence of the Grenz zone, which was seen on both ultrasound and histopathology. While HFUS has been used for various dermatological conditions, there is limited data available on its use for skin lymphomas. This case report highlights the potential use of HFUS as a non-invasive, repeatable, and objective monitoring tool for cutaneous lymphomas.