Fetal bone hypomineralization

case report

Abstract

Skeletal dysmorphologies are structural defects comprising different levels of disturbances in bone formation, which can range from a state of hypomineralization, mesomelia, to more intense changes, which present similar manifestations in intrauterine life. Skeletal dysplasia is suspected when the length of the long bones is below two standard deviations of the expected for gestational age and ultrasound is a diagnostic method of high sensitivity. In conclusion the accomplishment of the ultrasound examination is important for the early detection and diagnosis of the hypomineralization and to determine its extension still in the uterus, aiding in the prognosis and planning for treatments of these children.